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<h2><span style="color: #236fa1;">Primary Structure of tRNA -</span></h2>
<p style="text-align: justify;">The linear sequence of ribonucleotides that are linked by phosphodiester bonds is known as a primary structure of RNA. The phosphodiester bond formed between 3' OH of ribose sugar of one nucleotide and the 5' phosphate of another ribonucleotide.</p>
<h2 style="text-align: justify;"><span style="color: #236fa1;">Secondary Structure of tRNA -</span></h2>
<p style="text-align: justify;">tRNA molecule mostly forms a cloverleaf structure. tRNA is a 73-93 ribonucleotide chain and this chain folds into the cloverleaf-like secondary structure. In this structure arms loops and stem are found. A well-defined stem makes up an acceptor arm, D arm and loop, Anticodon arm and loop, and a single T-arm and loop. In all arms and loop numbering of ribonucleotides are usually conserved and constant. CCA sequence is present at the 3' end terminal position. In the anticodon loop, three anticodon bases are out in a prominent position. This anticodon region can base pair with the complementary codon on an mRNA. This leaf-like structure of tRNA allows the addition of an amino acid to the 3' end by the enzyme amino-acyl tRNA synthetase. The hydrogen bond stabilized the structure. The 2' structure of RNA is more stable than its 3' structure.</p>
<h2 style="text-align: justify;"><span style="color: #236fa1;">Tertiary Structure of tRNA -</span></h2>
<p style="text-align: justify;">In the tertiary structure of tRNA polyribonucleotides chain folded into a three-dimensional structure. Hydrogen bonds and hydrophobic interaction stabilize the 3&deg; tRNA and produce a compactly coiled globular structure. This compact coiled globular structure looks like the &lsquo;L&rsquo; shape.</p>
<p><img style="display: block; margin-left: auto; margin-right: auto;" src="https://vediphlie-aws.s3.ap-south-1.amazonaws.com/structure_of_t_RNA_9e17c3b321.PNG" alt="Structure of t-RNA" /></p>
<p style="text-align: center;">Fig.: Structure of t-RNA</p>

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In this tRNA topic of Biochemistry; we will cover the Primary Structure of tRNA, Secondary Structure of tRNA and Tertiary Structure of tRNA. 

tRNA - Primary, Secondary & Tertiary Structure of tRNA

Transfer ribonucleic acid (tRNA) is a type of RNA molecule that helps decode a messenger RNA (mRNA) sequence into a protein. In this tRNA topic of Biochemistry; we will cover the Primary Structure of tRNA, Secondary Structure of tRNA and Tertiary Structure of tRNA. 

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